Oncology Abstracts

Aggressive prostate cancer is characterized by altered lipid metabolism and metabolic stress. At a subcellular level these changes are localized to the endoplasmic reticulum (ER) and mitochondria. Traditionally the function of these organelles has been studied separately. A growing body of evidence shows that the interaction between mitochondria and ER at specialized membrane contact sites play a key role in regulating fundamental cellular processes such as lipid synthesis, mi...